Principal and CEO

Jeanne DiFrancesco is the Chief Executive Officer of ProOrbis, LLC, and acts as an executive advisor to a wide range of ventures in aerospace, cyber security/fraud detection, energy, and life sciences, Ms. DiFrancesco is one of the world’s leading experts in the economic valuation of intangibles including assets such as human capital, brands, technology, intellectual property and missions for the government and non-profit sectors.  With over 30 years of executive and strategic level experience, Ms. DiFrancesco has architected projects ranging in size and industry from the  International Space Station National Laboratory Reference Model to enterprise restructuring for leading private and public organizations in the health sciences, electronic materials, investment banking, insurance, financial operations, power generation, mining , logistics, electronic warfare and geospatial intelligence.

Ms. DiFrancesco authored the ProOrbis® Method, a breakthrough framework of strategic and economic techniques that combine a sophisticated understanding of long-range market vectors and insight on the real (tangible and intangible) assets of an enterprise to reposition organizations for dramatic performance improvement.  This methodology has been applied for almost two decades in real-world business situations ranging from the design of start-up operations to large scale enterprise transformations.  For more information visit

Ms. DiFrancesco serves on the board of the American Millennium Society.  She is a highly sought speaker and has served as an expert for various groups, including Harvard University, the National Space Society (NSS),  The Bankers Association for Finance and Trade (part of the ABA), The Conference Board, the Institute of Human Resource Information Management (IHRIM), the Wall Street Summit, the Brookings Institution, Drexel University, and continues as a long-time guest lecturer at the Wharton School.

Prior to ProOrbis, Ms. DiFrancesco served as a Principal Consultant at Price Waterhouse and as an executive at DuPont.  She holds an interdisciplinary undergraduate degree from the College of William and Mary and an MBA from the University of Pennsylvania’s Wharton School of Business.

 Selected Publications

“The Economics of Microgravity Research,” npj Microgravity, May 2015
“The International Space Station U.S. National Laboratory Reference Model,”
September 2010
“The Liability of Cost-Cutting: A CEO’s New Challenge” MRI Journal, May 2007



The ProOrbis® Method

The foundation for all ProOrbis work is the break-through strategic Framework and analytic techniques that redefine management science.

read more

Analytics Applications

ProOrbis® Analytics Applications are deployed in a wide variety of tools designed to support more intelligent decision-making.

read more